Monthly Archives: March 2010

H1N1 Update: ELEVATED influenza-like illness (ILI) now reported in CDC Regions 4, 7 and 9 Comments Off on H1N1 Update: ELEVATED influenza-like illness (ILI) now reported in CDC Regions 4, 7 and 9

From CDC’s most recent influenza surveillance report, week ending 20 March: “Elevated ILI was seen in Regions 4, 7 and 9. Region 4 is comprised of Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, and Tennessee. Region 7 is Iowa, Kansas, Missouri and Nebraska. And Region 9 is Arizona, California, Hawaii and Nevada. (Last […]

NIAID Press Release: Rapid Development of Drug-Resistant 2009 H1N1 Influenza Reported in Two Cases 1

FOR IMMEDIATE RELEASEFriday, March 26, 2010www.niaid.nih.gov Media Contact: Anne A. Oplinger(301) 402-1663niaidnews@niaid.nih.gov Rapid Development of Drug-Resistant 2009 H1N1 Influenza Reported in Two Cases Reevaluation of Treatment Strategies for Prolonged Infection Urged Two people with compromised immune systems who became ill with 2009 H1N1 influenza developed drug-resistant strains of virus after less than two weeks on […]

ELEVATED influenza-like illness (ILI) activity in CDC Region Four: AL, FL, GA, KY, MS, NC, SC, TN 2

CDC is reporting ELEVATED influenza-like illness (ILI) activity in Region Four, which includes: Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, and Tennessee. “Region 4 led the nation at the beginning of the fall wave, which largely followed school openings.” Region 4 also had a higher number of case counts of ILI on college […]

Investigation of Duke University cluster of oseltamivir-resistant H1N1 cases revealed patient-to-patient transmission of H275Y mutation; Health-care professionals had influenza symptoms 2

A multi-agency team of public health experts recently presented the results of their investigation into the cluster of four immunocompromised patients admitted to Duke University Medical Center over the 21-27 Sep, 2009 timeframe, who were found to have oseltamivir-resistant H1N1 (the H275Y mutation). Three of the patients died. The investigation involved reviews of patient medical […]

Op-Ed: Measuring the Impact of Pandemic H1N1 in “Years of Life Lost” still shows a Moderate Flu Burden 2

Pandemic H1N1 (pH1N1), as has been widely documented, has had a greater burden on younger populations. In a normal flu season, 90% of deaths are in persons over age 65. With pH1N1 the percentages have been nearly reversed with 88% of deaths occuring in persons under 65. Overall pH1N1 has exibited low pathogencity, resulting in […]

Research sheds new perspective on much-maligned 1976 swine flu (H1N1) vaccination campaign 1

A study published by scientists from the National Institutes of Health provides additional evidence that persons who received the 1976 vaccine may have immunity from pandeminc H1N1 (pH1N1). Researchers evaulated immune responses in mice after exposing them to several H1N1 viruses (1918, 1940, 1976 and 2009) and found that prior infection with a 1976 H1N1 […]

H1N1 in Transition: La persistance de dénouements Comments Off on H1N1 in Transition: La persistance de dénouements

As the traditional winter flu season peaks, pandemic H1N1 (pH1N1) activity in the USA remains at low ebb. Overall flu activity has remained below baseline for the last six weeks. Currently, pH1N1 is circulating at elevated (above baseline) levels in pockets of the southeastern and western regions of the country. Recent CDC estimates indicate that […]

Ferreting out pandemic H1N1 pathogenicity; Building a better mousetrap and H5N1 virus. 1

Thus far, H1N1 has exhibited moderate pathogenicity while proving efficient at transmission and replication. H5N1 by contrast is highly pathogenic, but has not evidenced capacity for sustained human-to-human transmission. This has been the human experience. It stands to reason, we would expect to see similar results when H1N1 is tested (in vivo) in other mammals. […]