Daily Archives: March 24, 2010

Investigation of Duke University cluster of oseltamivir-resistant H1N1 cases revealed patient-to-patient transmission of H275Y mutation; Health-care professionals had influenza symptoms 2

A multi-agency team of public health experts recently presented the results of their investigation into the cluster of four immunocompromised patients admitted to Duke University Medical Center over the 21-27 Sep, 2009 timeframe, who were found to have oseltamivir-resistant H1N1 (the H275Y mutation). Three of the patients died. The investigation involved reviews of patient medical […]

Op-Ed: Measuring the Impact of Pandemic H1N1 in “Years of Life Lost” still shows a Moderate Flu Burden 2

Pandemic H1N1 (pH1N1), as has been widely documented, has had a greater burden on younger populations. In a normal flu season, 90% of deaths are in persons over age 65. With pH1N1 the percentages have been nearly reversed with 88% of deaths occuring in persons under 65. Overall pH1N1 has exibited low pathogencity, resulting in […]