Tag Archives: International News

A Moderate Pandemic with Immoderate Impact ? 0

Acording to the latest CDC estimates, there have been just over 12,000 deaths from pandemic 2009 H1N1. This stands in contrast to the 36,000 deaths from a typical flu season, a number widely advertised by HHS. This, along with similar fatality rates were observed worldwide, has led some to describe the H1N1 pandemic as “moderate” [...]

Video Digest: H1N1 Retrospective; H1N1 Vaccines Discarded in CA; Weak H1N1 Vaccine Demand in Malaysia 1

 
 

H1N1 Research: On a “Heading” Toward a Universal Influenza Vaccine 2

When writing about influenza, it can be difficult to report on cutting-edge research. One has to carefully apply terms like “breakthrough.” One also has to avoid terms like “miracle cure.”
A universal flu vaccine, that can provide extended protection across a variety of recombitant influenza viruses represents the pinnacle for microbiological research in [...]

H1N1 Transitions: Three New H1N1 Variants Detected in India 1

ProMed mail reports on three new H1N1 variants detected by India’s National Institute of Virology (NIV). All the variants were treatable with the antiviral medication Oseltamivir (Tamiflu). Excerpt and references provided below:

Archive Number 20100525.1741
Published Date 25-MAY-2010
Subject PRO/AH Influenza pandemic (H1N1) (34): Indian variants
INFLUENZA PANDEMIC (H1N1) (34): INDIAN VARIANTS
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A ProMED-mail post
http://www.promedmail.org

ProMED-mail is a program [...]

H1N1 Lessons: Pandemic Influenza Vaccine Production Capacity: Ready for the Next Pandemic ? 1

The most significant failure in the global public health response to pandemic H1N1 was the lack of sufficient vaccine supplies in time for the second wave of H1N1.
According to reporting from the World Health Organization (WHO) H1N1 Influenza Vaccine Task Force, global influenza vaccine production continues to fall well short of WHO’s desired production targets [...]

Op-Ed: H1N1 Ebbs Worldwide, Legacies and Lessons Continue 1

With the passage of time, H1N1 has been quiet in the USA. No states have reported widespread or regional flu activity for five consecutive weeks. Doctor visits for Influenza-like Illness (ILI) are below baseline across all ten CDC regions.
On the international front, H1N1 has receded across much of the world. [...]

Investigation of Duke University cluster of oseltamivir-resistant H1N1 cases revealed patient-to-patient transmission of H275Y mutation; Health-care professionals had influenza symptoms 2

A multi-agency team of public health experts recently presented the results of their investigation into the cluster of four immunocompromised patients admitted to Duke University Medical Center over the 21-27 Sep, 2009 timeframe, who were found to have oseltamivir-resistant H1N1 (the H275Y mutation). Three of the patients died.
The investigation involved reviews of patient medical records [...]

Op-Ed: Measuring the Impact of Pandemic H1N1 in “Years of Life Lost” still shows a Moderate Flu Burden 3

Pandemic H1N1 (pH1N1), as has been widely documented, has had a greater burden on younger populations. In a normal flu season, 90% of deaths are in persons over age 65. With pH1N1 the percentages have been nearly reversed with 88% of deaths occuring in persons under 65.
Overall pH1N1 has exibited low pathogencity, resulting [...]

H1N1 in Transition: La persistance de dénouements 0

As the traditional winter flu season peaks, pandemic H1N1 (pH1N1) activity in the USA remains at low ebb. Overall flu activity has remained below baseline for the last six weeks. Currently, pH1N1 is circulating at elevated (above baseline) levels in pockets of the southeastern and western regions of the country. Recent CDC estimates indicate [...]

Ferreting out pandemic H1N1 pathogenicity; Building a better mousetrap and H5N1 virus. 1

Thus far, H1N1 has exhibited moderate pathogenicity while proving efficient at transmission and replication. H5N1 by contrast is highly pathogenic, but has not evidenced capacity for sustained human-to-human transmission. This has been the human experience. It stands to reason, we would expect to see similar results when H1N1 is tested (in vivo) in other mammals.

US [...]